Ambient PM2.5 and O3 and their combined effects on the onset of acute cardiovascular events: a time-stratified case-crossover study in Jining, China (2015–2023)
PM<sub>2.5</sub> and O<sub>3</sub> are risk factors for ACE onset, particularly on the day of onset and the day before. Moreover, we found no significant interaction of PM<sub>2.5</sub> and O<sub>3</sub> on ACE onset. Reducing PM<sub>2.5</sub> and O<sub>3</sub> concentrations and avoiding exposure to high levels of these pollutants in the early phase may mitigate ACE onset. Targeted policies aimed at reducing PM<sub>2.5</sub> and O<sub>3</sub> pollution should be developed to mitigate their adverse health effects among high-risk populations, including older adults and males.
Authors
- Xiujun Li (ORCID: https://orcid.org/0000-0001-7771-2725)
- Michael C. F. Tong (ORCID: https://orcid.org/0000-0002-9418-5223)
- C. Cheng
- Mei Wang (ORCID: https://orcid.org/0000-0002-3560-9460)
- Shufen Li (ORCID: https://orcid.org/0000-0003-4917-9278)
- Rui Xi (ORCID: https://orcid.org/0000-0002-6180-0795)
- Seung Hwan Song (ORCID: https://orcid.org/0000-0003-3247-3817)
- Rui Li (ORCID: https://orcid.org/0000-0003-1097-6683)
- Yu-Min Liang
- Qi Gao (ORCID: https://orcid.org/0000-0001-7245-3971)
Institutions
- Australian National University (AU)
- Shandong University (CN)
- Shandong Center for Disease Control and Prevention (CN)
Publication Details
- Journal
- BMC Public Health
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1186/s12889-025-25166-x
- Primary Topic
- Air Quality and Health Impacts
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Key Research and Development Program of China