Evaluation of Epicardial Adipose Tissue in Pediatric Patients with Chronic Kidney Diseases

Objective: Since with chronic kidney disease (CKD) is an inflammatory process, and disorders of uremia, calcium, and phosphorus metabolism are associated with cardiovascular disease (CVD), patients CKD are at high risk for developing CVDs.This study aims to evaluate epicardial adipose tissue (EAT) parameters which play an active role in the development of CVD and atherosclerosis in patients with CKD.Method: Twenty-seven CKD patients aged 0-18 and their age -matched 15 control patients were compared.Physical examination and laboratory findings of the patient group were recorded.Both groups evaluated EAT with M-mode echocardiographic measurements.Results: There was no difference between the 2 groups in terms of age, gender, and body mass index.EAT1, and EAT2 values were higher in the patient group, and these two measurements increased correlatedly as the CKD stage increased.Additionally, the correlation of EAT with blood phosphorus level and parathyroid hormone was evaluated. Conclusion:Cardiovascular morbidity and mortality are high in CKD.Therefore, early diagnosis is important.Evaluations of EAT and follow-ups at certain intervals can give us information in this sense as a non-invasive parameter.