Device encapsulated MSCs for adaptive secretome therapy to effectively target ischaemic heart injury

This translational study highlights a clinically viable, minimally invasive method for sustained cardioprotection, harnessing the MSC secretome to address a pivotal gap in current treatments for ischaemic heart disease.

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Publication Details

Journal
Stem Cell Research & Therapy
Published
2025-12-05
DOI
https://doi.org/10.1186/s13287-025-04847-9
Citations
1
Primary Topic
Tissue Engineering and Regenerative Medicine
Type
article
Field-Weighted Citation Impact
2.01
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article

Device encapsulated MSCs for adaptive secretome therapy to effectively target ischaemic heart injury

Rebecca H. Ritchie, Saba Naghipour, Thomas Loudovaris, Derek J. Hausenloy et al.
1 citations
Stem Cell Research & Therapy
Tissue Engineering and Regenerative Medicine
2.01
article

Device encapsulated MSCs for adaptive secretome therapy to effectively target ischaemic heart injury

Rebecca H. Ritchie, Saba Naghipour, Thomas Loudovaris, Derek J. Hausenloy, Kilian Kelly, Klearchos K. Papas, James J.H. Chong, David W. Greening, Anne M. Kong, Yali Deng, Janna Leigh Morrison, Shiang Y. Lim, Jarmon G. Lees, Jack R. T. Darby, Andrew R. Kompa, Tanya Hall, Cameron Kos, Jonathon Cross, Robert S. Phang, Lina Mariana, Andrew Newcomb, Ashley Nowland
article en
1 citations

Abstract

This translational study highlights a clinically viable, minimally invasive method for sustained cardioprotection, harnessing the MSC secretome to address a pivotal gap in current treatments for ischaemic heart disease.

Stem Cell Research & TherapyVol. 17(1)
The University of Sydney (AU), University of Arizona (US), Baker Heart and Diabetes Institute (AU), The University of Melbourne (AU), National University of Singapore (SG), University of Toronto (CA), La Trobe University (AU), Hospital for Sick Children (CA), Westmead Hospital (AU), SA Health (AU), Banner - University Medical Center Tucson (US), Duke-NUS Medical School (SG), SickKids Foundation (CA), Westmead Institute for Medical Research (AU), National Heart Centre Singapore (SG), Australian Centre for Heart Health (AU), Io Therapeutics (United States) (US), Melbourne Health (AU), University College London (GB), Monash University (AU), St Vincents Institute of Medical Research (AU)
Openalex Percentile: Top 10%
Tissue Engineering and Regenerative Medicine
2.01
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