Fabrication of testicular decellularized scaffolds using a hybrid SDS–supercritical CO₂ method: process optimization, extracellular matrix preservation, and biocompatibility evaluation
Despite the fact that the supercritical carbon dioxide protocol alone was unable to produce a decellularized scaffold with the desired standard characteristics, its combined use with 1% SDS not only reduced the decellularization time compared to other methods but also effectively preserved the extracellular matrix structures.
Authors
- Seyed Hadi Anjamrooz (ORCID: https://orcid.org/0000-0002-6200-6606)
- Ashraf Hassanpour (ORCID: https://orcid.org/0000-0002-4523-2716)
- Ali Zeinolabedini Hezave (ORCID: https://orcid.org/0000-0001-5285-3724)
- Fatemeh Hosseinpour
- Mojtaba Rastgou-Maeini
Institutions
- Imam Hossein University (IR)
- Iran University of Medical Sciences (IR)
- Shiraz University of Medical Sciences (IR)
- PNPE Company (Iran) (IR)
- Orano (United States) (US)
Publication Details
- Journal
- BioMedical Engineering OnLine
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1186/s12938-025-01477-3
- Primary Topic
- Tissue Engineering and Regenerative Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shiraz University of Medical Sciences
- Shiraz University