Biological aging and lifespan in men and women using a Mendelian randomization study

Telomere length and commonly used epigenetic clocks may not be an appropriate target for promoting lifespan. Instead, efforts to develop interventions for aging should target causal drivers of lifespan.

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Publication Details

Journal
Human Genomics
Published
2025-12-05
DOI
https://doi.org/10.1186/s40246-025-00852-4
Primary Topic
Epigenetics and DNA Methylation
Type
article
Field-Weighted Citation Impact
0.00
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article

Biological aging and lifespan in men and women using a Mendelian randomization study

C. Mary Schooling, Zhu Liduzi Jiesisibieke, Shun Li
Human Genomics
Epigenetics and DNA Methylation
article

Biological aging and lifespan in men and women using a Mendelian randomization study

C. Mary Schooling, Zhu Liduzi Jiesisibieke, Shun Li
article en

Abstract

Telomere length and commonly used epigenetic clocks may not be an appropriate target for promoting lifespan. Instead, efforts to develop interventions for aging should target causal drivers of lifespan.

Human GenomicsVol. 19(1)
The Graduate Center, CUNY (US), City University of New York (US), Capital Medical University (CN), Beijing Friendship Hospital (CN), University of Hong Kong (HK)
Openalex Percentile: Top 65%
Epigenetics and DNA Methylation
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