Hormonal and Cytokine Imbalances Promote a Proinflammatory Profile in Institutionalized Elderly
Institutionalization is associated with elevated blood hormone levels and an imbalanced cytokine pattern, indicating disruption of the neuroendocrine-immune network. These alterations align with the concept of inflammaging and highlight the impact of the living environment on immune-endocrine regulation in older adults.
Authors
- Wagner Batista dos Santos (ORCID: https://orcid.org/0000-0003-0090-2162)
- Adenilda Cristina Honório‐França (ORCID: https://orcid.org/0000-0002-0452-9804)
- Danielle Cristina Honório França (ORCID: https://orcid.org/0000-0002-4921-4064)
- Marcondes Alves Barbosa da Silva
- Gautam Dantas (ORCID: https://orcid.org/0000-0003-0455-8370)
- Patrícia Gelli Feres de Marchi (ORCID: https://orcid.org/0000-0001-7940-4478)
- Danny Laura Gomes Fagundes-Triches (ORCID: https://orcid.org/0000-0002-9971-1288)
- Laura Valdiane Luz Melo (ORCID: https://orcid.org/0000-0002-4074-2557)
- Eduardo Luzía França (ORCID: https://orcid.org/0000-0002-1854-5397)
- Arce dos Santos Sfredo
Institutions
- Universidade Federal de Rondônia (BR)
- Universidade Federal de Mato Grosso (BR)
- Universidade Estadual Paulista (Unesp) (BR)
Publication Details
- Journal
- Brain Sciences
- Published
- 2025-12-05
- DOI
- https://doi.org/10.3390/brainsci15121310
- Primary Topic
- Stress Responses and Cortisol
- Type
- article
- Field-Weighted Citation Impact
- 0.00