Adaptation of mtDNA content to endurance training, a cross-sectional study and an endurance training intervention
These findings align with previous research, indicating that mtDNA copy number correlates with VO<sub>2max</sub>, being higher in highly trained runners than in nontrained subjects, and increasing with training after a 6-week HIIT intervention. This study is novel in showing that a 6-week HIIT programme significantly boosts leukocyte mtDNA content, enhancing our understanding of individual adaptations to endurance training.
Authors
- Margarita Pérez (ORCID: https://orcid.org/0000-0001-7240-2082)
- Támara Iturriaga (ORCID: https://orcid.org/0000-0002-1073-7298)
- Iñigo Lorente
- Catalina Santiago (ORCID: https://orcid.org/0000-0003-3852-8217)
- Mar Larrosa (ORCID: https://orcid.org/0000-0002-8863-4686)
- Lara M. Munín Sánchez (ORCID: https://orcid.org/0000-0002-7042-578X)
- Thomas Yvert (ORCID: https://orcid.org/0000-0002-9451-9799)
Institutions
- Universidad Complutense de Madrid (ES)
- Research Institute Hospital 12 de Octubre (ES)
- Universidad Politécnica de Madrid (ES)
- Universidad Europea de Madrid (ES)
Publication Details
- Journal
- European Journal of Applied Physiology
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1007/s00421-025-06016-5
- Primary Topic
- Genetics and Physical Performance
- Type
- article
- Field-Weighted Citation Impact
- 0.00