Deep Learning-Based Lung Cancer Classification Using TNMCoding: Insights for Pharmacological Interventions
A multilevel deep learning approach known as TNM coding is commonly employed to classify lung cancer and predict disease stages. This method integrates multiple deep learning networks to address complex challenges effectively. The objective of this study is to categorize CT lung scans into three Tumor-Node-Metastasis (TNM) staging classes in accordance with the American Joint Committee on Cancer's (AJCC) guidelines and to explore how accurate classification can support targeted pharmacological interventions. Initially, different lung diseases , such as juxtapleural and internal nodules, are segmented automatically using an optimized conditional generative adversarial network (c-GAN). Following that, a combination of support vector machine classifiers and deep learning models is used to categorize tumors, nodes, and metastases based on the AJCC staging criteria. This automated TNM cataloging method provides accurate cancer staging without requiring manual detection of the region of interest (ROI) within CT scans. The proposed approach enhances the precision and cost-cost-effectiveness of CT scan analysis for lung cancer classification, thereby facilitating more tailored and effective pharmacological treatments.
Authors
- Kanchan Mahajan
- Diksha Chopade
- Monali Chaudhari
- Manish Rana (ORCID: https://orcid.org/0000-0003-3765-9821)
- Pravin Gawande (ORCID: https://orcid.org/0000-0003-3342-2368)
- Altaf O. Mulani
- Tilottama Dhake
Institutions
- Vels University (IN)
- University of Mumbai (IN)
- Institute of Engineering (NP)
- Shri Vishwakarma Skill University (IN)
- Sinhgad Dental College and Hospital (IN)
- K J Somaiya Medical College (IN)
- Bharati Vidyapeeth (Deemed to be University) (IN)
Publication Details
- Journal
- International Journal of Basic and Applied Sciences
- Published
- 2025-12-04
- DOI
- https://doi.org/10.14419/cvj7bm55
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00