Sintilimab as adjuvant therapy for high-risk hepatocellular carcinoma after curative resection: a multicentric retrospective cohort study

These findings support the potential of 6 months sintilimab monotherapy or in combination with TKIs as an effective adjuvant therapy for patients with HCC at high risk of recurrence. Further large-scale randomized controlled trials should be warranted.

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Publication Details

Journal
European Journal of Gastroenterology & Hepatology
Published
2025-11-26
DOI
https://doi.org/10.1097/meg.0000000000003080
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
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article

Sintilimab as adjuvant therapy for high-risk hepatocellular carcinoma after curative resection: a multicentric retrospective cohort study

Li-Xin Pan, Shuchang Chen, C. Chen, Wenxuan Liu et al.
European Journal of Gastroenterology & Hepatology
Hepatocellular Carcinoma Treatment and Prognosis
article

Sintilimab as adjuvant therapy for high-risk hepatocellular carcinoma after curative resection: a multicentric retrospective cohort study

Li-Xin Pan, Shuchang Chen, C. Chen, Wenxuan Liu, Jianbo Shao, Jia‐Yong Su, Dalong Yang, Ze Su, Jian‐Hong Zhong, Ning Peng, Xiaoling Xu, Rong‐Rui Huo, Shaoping Liu, Liang Ma, Xuan He, Pingping Guo, Zhu‐Jian Deng, Jun‐Jie Ou, Yi-Li Ma, Yi Zhang
article en

Abstract

These findings support the potential of 6 months sintilimab monotherapy or in combination with TKIs as an effective adjuvant therapy for patients with HCC at high risk of recurrence. Further large-scale randomized controlled trials should be warranted.

European Journal of Gastroenterology & HepatologyVol. 38(1)
Guangxi Medical University (CN), Wuzhou University (CN), Guigang City People's Hospital (CN), First Affiliated Hospital of GuangXi Medical University (CN), First People's Hospital of Nanning (CN)
Openalex Percentile: Top 50%
Hepatocellular Carcinoma Treatment and Prognosis
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