Protein-Protein Interactions in Papillary and Nonpapillary Urothelial Carcinoma Architectures: Comparative Study

We identified distinct PPI networks and the hub proteins specific to papillary and nonpapillary urothelial carcinomas. However, these findings are limited by the use of transcriptomic data and require experimental validation to confirm the functional relevance of the identified targets.

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Publication Details

Journal
JMIR Bioinformatics and Biotechnology
Published
2025-10-25
DOI
https://doi.org/10.2196/76736
Primary Topic
Bladder and Urothelial Cancer Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Protein-Protein Interactions in Papillary and Nonpapillary Urothelial Carcinoma Architectures: Comparative Study

Sean Hacking, Ece D. Gamsiz Uzun, Charissa Chou, Ali Amin et al.
JMIR Bioinformatics and Biotechnology
Bladder and Urothelial Cancer Treatments
article

Protein-Protein Interactions in Papillary and Nonpapillary Urothelial Carcinoma Architectures: Comparative Study

Sean Hacking, Ece D. Gamsiz Uzun, Charissa Chou, Ali Amin, Alper Uzun, Yiğit Baykara, Liang Cheng C
article en

Abstract

We identified distinct PPI networks and the hub proteins specific to papillary and nonpapillary urothelial carcinomas. However, these findings are limited by the use of transcriptomic data and require experimental validation to confirm the functional relevance of the identified targets.

JMIR Bioinformatics and BiotechnologyVol. 6
University of Arizona (US), Brown University (US), Rhode Island Hospital (US), New York University (US)
Openalex Percentile: Top 42%
Bladder and Urothelial Cancer Treatments
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