Comparative evaluation of lipid-based nanocarriers encapsulating enriched astaxanthin extract from <i>haematococcus pluvialis</i> : preparation, characterization, and UVB protection
Three successfully optimized Nano-ATXex formulations protected against UVB-induced DNA damage and senescence in vitro and alleviated skin damage in vivo, with NLC-ATXex showing the highest efficacy. The differences in cytocompatibility and biological activities indicated the importance of selecting an appropriate lipid-based nanocarrier formulation. These findings support the potential of ATXex-loaded nanocarriers in skin protection applications.
Authors
- Le Hoang Sinh (ORCID: https://orcid.org/0000-0002-8540-9010)
- Ngoc-Bich-Dao Vu (ORCID: https://orcid.org/0000-0002-0171-4481)
- Dai‐Nghiep Ngo (ORCID: https://orcid.org/0000-0002-7177-6557)
- Lê Minh Giang (ORCID: https://orcid.org/0000-0003-3370-4453)
- Minh-Hiep Nguyen (ORCID: https://orcid.org/0000-0002-8441-5769)
- Thi-Ngoc-Mai Tran
Institutions
- Vietnam National University Ho Chi Minh City (VN)
- Ho Chi Minh City University of Science (VN)
- University of Da Nang (VN)
- Department of Biotechnology (IN)
- Dalat University (VN)
- Institute for Nuclear Science and Technology (VN)
Publication Details
- Journal
- International Journal of Radiation Biology
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1080/09553002.2025.2595627
- Citations
- 1
- Primary Topic
- Advancements in Transdermal Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.79