Patients with ulcerative colitis that have endoscopic Mayo score 1 and active histologic inflammation have similar outcomes to mild-moderate patients with Mayo score 2: a post hoc analysis of the VARSITY trial
Patients with histologically active MES 1 had comparable clinical and histologic outcomes at week 52 as those with conventional mild-moderate UC, suggesting that histology may better predict prognosis than symptoms or endoscopy alone.
Authors
- Emily C L Wong (ORCID: https://orcid.org/0000-0001-9472-201X)
- Walter Reinisch (ORCID: https://orcid.org/0000-0002-2088-091X)
- John K. Marshall (ORCID: https://orcid.org/0000-0002-0523-9032)
- Parambir S. Dulai (ORCID: https://orcid.org/0000-0002-9514-2321)
- Neeraj Narula (ORCID: https://orcid.org/0000-0002-1536-8436)
- Vipul Jairath (ORCID: https://orcid.org/0000-0003-1590-0338)
- Nazir Ahmad Khan (ORCID: https://orcid.org/0000-0003-0826-8952)
Institutions
- Northwestern University (US)
- Western University (CA)
- Population Health Research Institute (CA)
- Medical University of Vienna (AT)
- McMaster University (CA)
Publication Details
- Journal
- European Journal of Gastroenterology & Hepatology
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1097/meg.0000000000003092
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00