Publicly Available <i>Neisseria Gonorrhoeae</i> Genomes Predominantly Represent In Vitro-Derived Nonpiliated Variants
All N. gonorrhoeae strains possess the genes necessary for pilin AV; however, most genomic sequences were derived from nonpiliated variants that emerged during in vitro culture through reversible pilus phase variation and irreversible deletion of the pilE gene.
Authors
- Iryna Boiko (ORCID: https://orcid.org/0000-0001-7065-8666)
- H. Steven Seifert (ORCID: https://orcid.org/0000-0001-8651-0375)
- Selma Metaane (ORCID: https://orcid.org/0000-0002-2543-1646)
Institutions
- Northwestern University (US)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1093/infdis/jiaf557
- Citations
- 1
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 1.18