Nanoparticle-based co-delivery of ciprofloxacin and meropenem enhances synergistic activity against multidrug-resistant hypervirulent <i>Klebsiella pneumoniae</i> clinical isolates
Dual antibiotic-loaded nanoparticles represent an innovative therapeutic approach against hvKP infections and highlight nanotechnology's potential in overcoming MDR pathogens for future clinical application.
Authors
- Sherine A. Aly (ORCID: https://orcid.org/0000-0002-4486-325X)
- Safy Hadiya (ORCID: https://orcid.org/0000-0002-8105-4531)
- Ahmed S. Ahmed (ORCID: https://orcid.org/0000-0003-3794-8295)
- Shereen Rashad Mohammed
- Reham M. Mostafa
Institutions
- Chest Diseases Hospital (KW)
- Assiut University Hospitals (EG)
- Chest Hospital, Ministry of Health and Welfare (TW)
- Assiut University (EG)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1093/jac/dkaf422
- Primary Topic
- Nanoparticle-Based Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00