Diagnosis, risk stratification, and early management of non-ST-segment elevation acute coronary syndrome

Non-ST-segment elevation acute coronary syndrome (NSTE-ACS) represents a unique clinical syndrome, comprising non-ST-segment elevation myocardial infarction (NSTEMI) and unstable angina. NSTEMI, as the more common and serious form of NSTE-ACS, is particularly noteworthy because of its diverse clinical presentation, electrocardiogram changes, and angiography findings, which may pose challenges in diagnosis and treatment and may subsequently influence prognosis. This review offers a comprehensive overview of current evidence-based approaches to NSTE-ACS management, focusing on diagnosis, risk stratification, and treatment strategies while highlighting emerging trends and ongoing challenges in optimising patient outcomes.

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Publication Details

Journal
EuroIntervention
Published
2025-11-24
DOI
https://doi.org/10.4244/eij-d-25-00100
Citations
1
Primary Topic
Acute Myocardial Infarction Research
Type
article
Field-Weighted Citation Impact
1.39
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Diagnosis, risk stratification, and early management of non-ST-segment elevation acute coronary syndrome

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article

Diagnosis, risk stratification, and early management of non-ST-segment elevation acute coronary syndrome

Philippe Gabríel Steg, Vijay Kunadian, M Kovacevic, Daniel A. Jones, Holger Thiele
article en
1 citations

Abstract

Non-ST-segment elevation acute coronary syndrome (NSTE-ACS) represents a unique clinical syndrome, comprising non-ST-segment elevation myocardial infarction (NSTEMI) and unstable angina. NSTEMI, as the more common and serious form of NSTE-ACS, is particularly noteworthy because of its diverse clinical presentation, electrocardiogram changes, and angiography findings, which may pose challenges in diagnosis and treatment and may subsequently influence prognosis. This review offers a comprehensive overview of current evidence-based approaches to NSTE-ACS management, focusing on diagnosis, risk stratification, and treatment strategies while highlighting emerging trends and ongoing challenges in optimising patient outcomes.

EuroInterventionVol. 21(23)
Inserm (FR), Queen Mary University of London (GB), University of Novi Sad (RS), Université Paris Cité (FR), Barts Health NHS Trust (GB), Newcastle upon Tyne Hospitals NHS Foundation Trust (GB), Freeman Hospital (GB), Assistance Publique – Hôpitaux de Paris (FR), Leipzig Heart Institute (DE), Institute for Cardiovascular Diseases of Vojvodina (RS), Hôpital Bichat-Claude-Bernard (FR), Newcastle University (GB), Leipzig University (DE)
Openalex Percentile: Top 13%
Acute Myocardial Infarction Research
1.39
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