Efficacy and safety of tenapanor in the management of irritable bowel syndrome with constipation: a systematic review and meta-analysis

Tenapanor is effective in improving IBS-C symptoms but has a higher incidence of treatment-related AEs. Further studies are needed to evaluate its long-term safety.

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Publication Details

Journal
European Journal of Gastroenterology & Hepatology
Published
2025-11-26
DOI
https://doi.org/10.1097/meg.0000000000003107
Primary Topic
Gastrointestinal motility and disorders
Type
article
Field-Weighted Citation Impact
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article

Efficacy and safety of tenapanor in the management of irritable bowel syndrome with constipation: a systematic review and meta-analysis

Nikki Duong, Dushyant Singh Dahiya, Islam Mohamed, Ahmed Aref et al.
European Journal of Gastroenterology & Hepatology
Gastrointestinal motility and disorders
article

Efficacy and safety of tenapanor in the management of irritable bowel syndrome with constipation: a systematic review and meta-analysis

Nikki Duong, Dushyant Singh Dahiya, Islam Mohamed, Ahmed Aref, Hassan Ghoz, Hazem Abosheaishaa, Ahmed Eltelbany, Mohamed A. Aldemerdash, Abdallfatah Abdallfatah
article en

Abstract

Tenapanor is effective in improving IBS-C symptoms but has a higher incidence of treatment-related AEs. Further studies are needed to evaluate its long-term safety.

European Journal of Gastroenterology & Hepatology
University of Maryland, Baltimore (US), Brooklyn Hospital Center (US), University of Kansas (US), University of New Mexico (US), Beaumont Hospital, Royal Oak (US), Beaumont Hospital, Troy (US), October 6 University (EG), University of Maryland, College Park (US), University of Missouri (US), Stanford University (US), Sohag University (EG)
Openalex Percentile: Top 46%
Gastrointestinal motility and disorders
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Efficacy and safety of tenapanor in the management of irritable bowel syndrome with constipation: a systematic review and meta-analysis — Nikki Duong, Dushyant Singh Dahiya, et al. · European Journal of Gastroenterology & Hepatology (2025) | TGRS Research Map | TGRS