Antithrombotic strategies after transcatheter edge-to-edge repair: clinical implications from the MitraSafe study
SAPT was associated with improved 12-month survival and a lower rate of bleeding events compared with DAPT in patients undergoing TEER. While individual rates of major and minor bleeding were not significantly different, the overall bleeding burden was reduced in the SAPT group. These findings suggest a potential association between SAPT and lower mortality rates and support its consideration in patients at high bleeding risk. Further prospective studies are warranted to confirm these observations.
Authors
- Giorgia Marsili
- Francesco Barillà
- Valeria Cammalleri (ORCID: https://orcid.org/0000-0001-5374-8125)
- Gaetano Idone
- Giulia Manni
- Saverio Muscoli (ORCID: https://orcid.org/0000-0002-4037-7561)
- Massimo Marchei
- Giuseppe Sangiorgi (ORCID: https://orcid.org/0000-0001-5862-1967)
- Dalgisio Lecis (ORCID: https://orcid.org/0000-0001-5795-6028)
Institutions
- University of Rome Tor Vergata (IT)
- Cluster in Biomedicine (IT)
- Biomed Research Institute (US)
- Institute for Biomedicine (IT)
Publication Details
- Journal
- Journal of Cardiovascular Medicine
- Published
- 2025-11-06
- DOI
- https://doi.org/10.2459/jcm.0000000000001792
- Citations
- 1
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39