Kidney Function, Alzheimer Disease Blood Biomarkers, and Dementia Risk in Community-Dwelling Older Adults
Impaired kidney function was associated with elevated circulating level of most AD blood biomarkers. However, the presence of impaired kidney function did not independently increase the risk of dementia but rather seemed to accelerate the clinical expression of underlying neurodegenerative pathology.
Authors
- Amaia Calderón‐Larrañaga (ORCID: https://orcid.org/0000-0001-9064-9222)
- Laura Fratiglioni (ORCID: https://orcid.org/0000-0002-6374-6614)
- Claudia Fredolini (ORCID: https://orcid.org/0000-0002-7674-2014)
- Debora Rizzuto (ORCID: https://orcid.org/0000-0001-6199-9629)
- Martina Valletta (ORCID: https://orcid.org/0000-0003-0139-8287)
- Giorgi Beridze (ORCID: https://orcid.org/0000-0002-2615-226X)
- Matilda Dale (ORCID: https://orcid.org/0000-0002-5788-7744)
- Davide Liborio Vetrano (ORCID: https://orcid.org/0000-0002-3099-4830)
- Bengt Winblad (ORCID: https://orcid.org/0000-0002-0011-1179)
- Giulia Grande (ORCID: https://orcid.org/0000-0001-6312-3815)
- Francesca Gasparini (ORCID: https://orcid.org/0009-0004-3818-9176)
Institutions
- Karolinska University Hospital (SE)
- Stockholm University (SE)
- Science for Life Laboratory (SE)
- Karolinska Institutet (SE)
- Stockholm Gerontology Research Center Foundation (SE)
- KTH Royal Institute of Technology (SE)
Publication Details
- Journal
- Neurology
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1212/wnl.0000000000214446
- Citations
- 4
- Primary Topic
- Dialysis and Renal Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 5.72