Laparoscopic versus open distal gastrectomy with D2 lymphadenectomy following neoadjuvant chemotherapy for locally advanced gastric cancer (CLASS-03b): protocol for a multicentre, randomised, controlled, non-inferiority trial
Chinese Clinical Trial Registry, ChiCTR2500109677; registered on 23 September 2025. Protocol V.2.1, dated 29 June 2025.
Authors
- Yujian Zeng (ORCID: https://orcid.org/0000-0001-5398-8073)
- Jian‐Kun Hu (ORCID: https://orcid.org/0000-0002-3294-3471)
- Yan Shi (ORCID: https://orcid.org/0000-0003-0388-5433)
- Yuqing Liang (ORCID: https://orcid.org/0000-0001-8421-752X)
- Su Yan
- Wenqing Hu (ORCID: https://orcid.org/0000-0001-5161-3980)
- Changqing Jing (ORCID: https://orcid.org/0000-0002-3933-3721)
- Zhigang Deng
- Lu Zang
- Gaoping Zhao (ORCID: https://orcid.org/0000-0001-5899-9230)
- Zaisheng Ye (ORCID: https://orcid.org/0000-0001-9881-6400)
- Guoxin Li (ORCID: https://orcid.org/0000-0003-2773-7048)
- Zekuan Xu (ORCID: https://orcid.org/0000-0001-5179-4128)
- Yong Fan (ORCID: https://orcid.org/0000-0003-4813-7017)
- Kun Yang (ORCID: https://orcid.org/0000-0002-8891-5736)
- Bo Wei (ORCID: https://orcid.org/0000-0002-3755-6542)
- Xiaolong Chen (ORCID: https://orcid.org/0000-0003-1566-6975)
- Bin Zhang (ORCID: https://orcid.org/0000-0002-2970-746X)
- Jian Zhang (ORCID: https://orcid.org/0000-0002-6558-791X)
- Quan Wang (ORCID: https://orcid.org/0000-0001-6727-1508)
- Guihua Wang (ORCID: https://orcid.org/0000-0002-3624-6390)
- Xuefei Wang (ORCID: https://orcid.org/0000-0002-2645-0953)
- Jin Zhou (ORCID: https://orcid.org/0000-0001-6535-9426)
- Kun Qian (ORCID: https://orcid.org/0009-0003-9247-2901)
- Heli Liu (ORCID: https://orcid.org/0000-0002-3443-6174)
- Kaixiong Tao (ORCID: https://orcid.org/0000-0002-3356-3091)
- Weihan Zhang (ORCID: https://orcid.org/0000-0002-9498-8245)
- Xiangdong Cheng
- Jingyu Deng (ORCID: https://orcid.org/0009-0006-3894-6995)
- Xianli He
Institutions
- Central South University (CN)
- University of Electronic Science and Technology of China (CN)
- Army Medical University (CN)
- Jilin University (CN)
- Changzhi Medical College (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Sichuan University (CN)
- Fudan University (CN)
- Kunming Medical University (CN)
- Ruijin Hospital (CN)
- Chinese PLA General Hospital (CN)
- Soochow University (CN)
- Qinghai University Affiliated Hospital (CN)
- Mianyang Central Hospital (CN)
- Zhejiang Cancer Hospital (CN)
- Shandong Provincial Hospital (CN)
- Sichuan Cancer Hospital (CN)
- First Affiliated Hospital of Kunming Medical University (CN)
- Lanzhou University Second Hospital (CN)
- First Hospital of Jilin University (CN)
- Zhongshan Hospital (CN)
- Wuhan Union Hospital (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Southwest Hospital (CN)
- Henan Cancer Hospital (CN)
- Ministry of Education (ET)
- Fujian Provincial Cancer Hospital (CN)
- First Affiliated Hospital of Soochow University (CN)
- Beijing Tsinghua Chang Gung Hospital (CN)
- Tang Du Hospital (CN)
- Xiangya Hospital Central South University (CN)
- Tongji Hospital (CN)
- Shandong First Medical University (CN)
- Union Hospital (CN)
- First Affiliated Hospital Zhejiang University (CN)
- Huazhong University of Science and Technology (CN)
- Lanzhou University (CN)
- Nanjing Medical University (CN)
- Chongqing Medical University (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- BMJ Open
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1136/bmjopen-2025-111576
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Sichuan University
- West China Hospital, Sichuan University