The Prognostic Significance of <scp>LINC00638</scp> in Lumbar Disc Herniation and Its Effect on Senescence of Nucleus Pulposus Cells
Serum LINC00638 holds promise as a potential biomarker for the diagnosis and prognostic evaluation of LDH, closely reflecting disease severity. Furthermore, LINC00638 participates in regulating hNPCs' senescence and LDH progression by modulating miR-185-5p.
Authors
- Wei He (ORCID: https://orcid.org/0000-0001-8909-9008)
- Shiqing Xu (ORCID: https://orcid.org/0000-0001-9921-3361)
- Zhen Wang (ORCID: https://orcid.org/0000-0002-7558-937X)
- Xijing He (ORCID: https://orcid.org/0009-0001-7491-1398)
- Yanhua Sun
- Haishan Xu (ORCID: https://orcid.org/0000-0003-4306-8032)
- Jichen Liu
Institutions
- People's Liberation Army 401 Hospital (CN)
- Ningxia Medical University (CN)
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
- Ningxia Medical University General Hospital (CN)
- The Fourth People's Hospital of Ningxia Hui Autonomous Region (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- JOR Spine
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/jsp2.70138
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00