Chronic Diarrhoea in Hyperthyroidism Leading to Rectal Prolapse: A Case Report

Rectal prolapse is typically associated with chronic constipation and pelvic floor dysfunction. However, its occurrence secondary to chronic diarrhoea from hyperthyroidism is exceptionally rare. This case emphasises a rarely discussed pathophysiological link between prolonged thyrotoxicosis and advanced rectal prolapse. In this report, a 67-year-old male presented with chronic diarrhoea and rectal prolapse for two years, along with classic hyperthyroid features like weight loss and a longstanding multinodular goitre. Clinical and hormonal evaluation confirmed uncontrolled hyperthyroidism, while local examination revealed Grade V rectal prolapse. Imaging and endoscopic workup ruled out malignancy or other structural causes. He was managed conservatively with antithyroid drugs, dietary changes, and pelvic floor rehabilitation. Uncontrolled hyperthyroidism can present atypically with advanced rectal prolapse due to persistent diarrheal episodes and weakened pelvic support. Early recognition, endocrine optimisation, and multidisciplinary care are pivotal in such rare yet clinically significant presentations.

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Publication Details

Journal
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Published
2025-12-05
DOI
https://doi.org/10.7860/jcdr/2026/80793.22333
Primary Topic
Pelvic floor disorders treatments
Type
article
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article

Chronic Diarrhoea in Hyperthyroidism Leading to Rectal Prolapse: A Case Report

Manoj Jose, Samina Ruquaya, Najeem Fazil, K Vivekananda Subramania Nathan
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Pelvic floor disorders treatments
article

Chronic Diarrhoea in Hyperthyroidism Leading to Rectal Prolapse: A Case Report

Manoj Jose, Samina Ruquaya, Najeem Fazil, K Vivekananda Subramania Nathan
article en

Abstract

Rectal prolapse is typically associated with chronic constipation and pelvic floor dysfunction. However, its occurrence secondary to chronic diarrhoea from hyperthyroidism is exceptionally rare. This case emphasises a rarely discussed pathophysiological link between prolonged thyrotoxicosis and advanced rectal prolapse. In this report, a 67-year-old male presented with chronic diarrhoea and rectal prolapse for two years, along with classic hyperthyroid features like weight loss and a longstanding multinodular goitre. Clinical and hormonal evaluation confirmed uncontrolled hyperthyroidism, while local examination revealed Grade V rectal prolapse. Imaging and endoscopic workup ruled out malignancy or other structural causes. He was managed conservatively with antithyroid drugs, dietary changes, and pelvic floor rehabilitation. Uncontrolled hyperthyroidism can present atypically with advanced rectal prolapse due to persistent diarrheal episodes and weakened pelvic support. Early recognition, endocrine optimisation, and multidisciplinary care are pivotal in such rare yet clinically significant presentations.

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Openalex Percentile: Top 45%
Pelvic floor disorders treatments
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