RAB40C recruiting TRIM21 facilitates the progression of hepatocellular carcinoma by stabilizing EGFR
This research, we identified that RAB40C, an oncogene, was a target of STAT3 and boosted the malignant progression of HCC by regulation of EGFR cascades, and exerted a promising potential in HCC therapy.
Authors
- Doudou Wen
- Hui Li (ORCID: https://orcid.org/0000-0002-3526-6664)
- Shubing Zhang (ORCID: https://orcid.org/0000-0003-2819-8023)
- Xiaotang Di (ORCID: https://orcid.org/0000-0002-7350-8978)
- Zhixiong Dong (ORCID: https://orcid.org/0000-0001-7281-671X)
- Ru‐Ping Dai (ORCID: https://orcid.org/0000-0002-1027-6698)
- Yang Wang (ORCID: https://orcid.org/0000-0002-0078-8585)
- Jinhua Yan
- Hao Jiang (ORCID: https://orcid.org/0000-0001-7270-1939)
- Jianing Zhao (ORCID: https://orcid.org/0000-0002-7921-3409)
- Rongji Yu
- Qiao Xu (ORCID: https://orcid.org/0000-0001-8619-6777)
- Lili Shao (ORCID: https://orcid.org/0000-0003-4213-0746)
Institutions
- Central South University (CN)
- Wenzhou Medical University (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1186/s12964-025-02580-7
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00