Biological aging and gout risk in hyperuricemia: a UK Biobank cohort study
These findings suggest that biological aging acceleration represents a risk factor for the progression from hyperuricemia to gout, thus highlighting a new strategy and approach to manage hyperuricemia and prevent gout through healthy aging approaches.
Authors
- Xiaoxia Zhu (ORCID: https://orcid.org/0000-0003-3030-0306)
- Jiayan Zhou (ORCID: https://orcid.org/0000-0001-5974-087X)
- Themistocles L. Assimes (ORCID: https://orcid.org/0000-0003-2349-0009)
- Jigao Sun (ORCID: https://orcid.org/0000-0001-8994-8559)
- Zhiying Chen (ORCID: https://orcid.org/0000-0001-6020-4484)
- Benjun Wei
- Jing Yu (ORCID: https://orcid.org/0000-0002-2903-1340)
- Ningfei Li (ORCID: https://orcid.org/0000-0003-3315-3591)
- Yige Li (ORCID: https://orcid.org/0000-0003-3690-7299)
- Aling Shen (ORCID: https://orcid.org/0000-0002-5081-3523)
- Nardeen Ayad (ORCID: https://orcid.org/0000-0002-1482-7792)
- Yanyu Yang
- Ao Shang (ORCID: https://orcid.org/0000-0001-7627-628X)
- Yuanyuan Sun (ORCID: https://orcid.org/0000-0002-2310-1862)
- Hui Zhang (ORCID: https://orcid.org/0000-0002-6331-6876)
- Jinlin Li (ORCID: https://orcid.org/0000-0002-8998-9278)
- Fang Zhou (ORCID: https://orcid.org/0000-0002-7955-6014)
- Fei Lin (ORCID: https://orcid.org/0000-0003-0130-9985)
- Yuke Teng (ORCID: https://orcid.org/0000-0001-5016-4706)
- Guang Chen
- Zhi'ang Cheng
- Man Han
- Xiangjun Yin
- Litao Bai
- Ying Wu (ORCID: https://orcid.org/0000-0002-3770-0970)
Institutions
- Broad Institute (US)
- Zhejiang Chinese Medical University (CN)
- Fujian University of Traditional Chinese Medicine (CN)
- Harvard University (US)
- Cairo University (EG)
- Beijing University of Chinese Medicine (CN)
- Dalian Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Fudan University (CN)
- Liaoning University of Traditional Chinese Medicine (CN)
- Harvard University Press (US)
- Gansu University of Traditional Chinese Medicine (CN)
- Qinghai No.3 People's Hospital (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- Integrated Chinese Medicine (China) (HK)
- Hubei 672 Orthopedics Hospital of Traditional Chinese Medicine and Western Medicine (CN)
- Harvard Pilgrim Health Care (US)
- First Affiliated Hospital of Xinxiang Medical University (CN)
- Affiliated Hospital of Shaanxi University of Chinese Medicine (CN)
- Affiliated Hospital of Liaoning University of Traditional Chinese Medicine (CN)
- Guangdong Academy of Medical Sciences (CN)
- Guang’anmen Hospital (CN)
- Qinghai Provincial Peoples Hospital (CN)
- Guangdong Provincial People's Hospital (CN)
- Huashan Hospital (CN)
- Guangdong Provincial Family Planning Hospital (CN)
- First Affiliated Hospital of Jinan University (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
- Southern Medical University (CN)
- Henan Medical University (CN)
- Chongqing Medical University (CN)
- University of Hong Kong (HK)
- Stanford University (US)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1097/js9.0000000000003948
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 0.00