Gender-age-physiology stage and body mass index are useful predictors of nintedanib discontinuation and prognosis in patients with idiopathic pulmonary fibrosis and progressive fibrotic interstitial lung diseases
GAP stage and BMI can be useful for predicting prognosis and future nintedanib discontinuation in patients with IPF and PF-ILDs. Nintedanib treatment may be considered in patients with IPF and PF-ILDs in an earlier stage of the disease.
Authors
- Kai Yazaki (ORCID: https://orcid.org/0000-0002-6566-6140)
- Shigen Hayashi
- Takeo Endo
- Yukio Ishii (ORCID: https://orcid.org/0000-0002-3475-181X)
- Takeshi Kawakami (ORCID: https://orcid.org/0000-0001-9385-9516)
- Tohru Sakamoto (ORCID: https://orcid.org/0000-0002-8876-1466)
- Hiroaki Iijima (ORCID: https://orcid.org/0000-0003-4621-2394)
- Masashi Matsuyama (ORCID: https://orcid.org/0000-0002-8880-6951)
- Takayuki Kaburagi
- Hiroaki Satoh
- Norihiro Kikuchi
- Kunihiko Miyazaki
- Naoki Arai
- Toshiaki Motegi
- Nobuyuki Hizawa
Institutions
- University of Tsukuba (JP)
- National Hospital Organization Mito Medical Center (JP)
- Tsukuba Memorial Hospital (JP)
- Sakai Municipal Hospital (JP)
- National Hospital Organization (JP)
- Ibaraki Prefectural Central Hospital (JP)
- Tsukuba Medical Center Hospital (JP)
- Kasumigaura Medical Center (JP)
- Ibarakihigashi National Hospital (JP)
- Kobari General Hospital (JP)
Publication Details
- Journal
- BMC Pulmonary Medicine
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1186/s12890-025-04048-3
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00