Systematic differences in TB treatment outcomes across Brazil by patient- and area-related factors: an analysis of national disease registry data
Our analysis revealed substantial variation in TB treatment outcomes across states and municipalities, with only a minority attributable to patient-level factors. Area-level variation likely reflects consequences of differences in health system organisation or socio-environmental factors not reflected in patient-level data. Further research on these factors is needed to identify effective approaches to TB care, reduce geographic disparities and improve treatment outcome.
Authors
- Mauro Niskier Sanchez (ORCID: https://orcid.org/0000-0002-0472-1804)
- Ethel Leonor Nóia Maciel (ORCID: https://orcid.org/0000-0003-4826-3355)
- Márcia C. Castro (ORCID: https://orcid.org/0000-0003-4606-2795)
- Fernanda Dockhorn Costa Johansen (ORCID: https://orcid.org/0000-0002-1762-9484)
- Patrícia Bartholomay Oliveira
- Kleydson Alves
- Daniele Maria Pelissari (ORCID: https://orcid.org/0000-0002-0760-1875)
- Ted Cohen (ORCID: https://orcid.org/0000-0002-8091-7198)
- Nicolas A. Menzies (ORCID: https://orcid.org/0000-0002-2571-016X)
- Do Kyung Ryuk (ORCID: https://orcid.org/0000-0001-8067-968X)
- Luiza Ohana Harada (ORCID: https://orcid.org/0009-0005-6165-5232)
Institutions
- Seoul National University (KR)
- Universidade de Brasília (BR)
- Yale University (US)
- Pan American Health Organization (Brasil) (BR)
- Ministério da Saúde (BR)
- Harvard Global Health Institute (US)
Publication Details
- Journal
- BMJ Global Health
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1136/bmjgh-2024-018822
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health