Trachealisation of the Oesophagus in Lymphocytic Oesophagitis: An Uncommon Endoscopic Presentation

Lymphocytic oesophagitis (LyE) is a rare histopathological diagnosis with variable and often non-specific endoscopic features. Oesophageal rings and trachealisation are typically associated with eosinophilic oesophagitis but are uncommonly described in LyE. We describe a 79-year-old woman who presented with progressive dysphagia and unintentional weight loss. Endoscopic examination demonstrated trachealisation of the oesophagus, while histopathological evaluation confirmed florid lymphocytic oesophagitis with apoptotic keratinocytes. The patient exhibited only partial symptom relief with proton pump inhibitor (PPI) therapy; however, induction with swallowed budesonide resulted in marked clinical improvement and weight stabilisation. This case highlights an unusual endoscopic manifestation of LyE, expanding the recognised phenotypic spectrum of this entity and emphasising the essential role of histopathological evaluation in distinguishing oesophagitis subtypes.

Authors

Institutions

Publication Details

Journal
Cureus
Published
2025-12-05
DOI
https://doi.org/10.7759/cureus.98507
Primary Topic
Eosinophilic Esophagitis
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Trachealisation of the Oesophagus in Lymphocytic Oesophagitis: An Uncommon Endoscopic Presentation

Kashif Hameed, M Andrew, Murshid Ali Mohamed Maheen
Cureus
Eosinophilic Esophagitis
article

Trachealisation of the Oesophagus in Lymphocytic Oesophagitis: An Uncommon Endoscopic Presentation

Kashif Hameed, M Andrew, Murshid Ali Mohamed Maheen
article en

Abstract

Lymphocytic oesophagitis (LyE) is a rare histopathological diagnosis with variable and often non-specific endoscopic features. Oesophageal rings and trachealisation are typically associated with eosinophilic oesophagitis but are uncommonly described in LyE. We describe a 79-year-old woman who presented with progressive dysphagia and unintentional weight loss. Endoscopic examination demonstrated trachealisation of the oesophagus, while histopathological evaluation confirmed florid lymphocytic oesophagitis with apoptotic keratinocytes. The patient exhibited only partial symptom relief with proton pump inhibitor (PPI) therapy; however, induction with swallowed budesonide resulted in marked clinical improvement and weight stabilisation. This case highlights an unusual endoscopic manifestation of LyE, expanding the recognised phenotypic spectrum of this entity and emphasising the essential role of histopathological evaluation in distinguishing oesophagitis subtypes.

CureusVol. 17(12)
University Hospitals Birmingham NHS Foundation Trust (GB)
Openalex Percentile: Top 42%
Eosinophilic Esophagitis
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.