High-level biocontainment laboratories: risks and necessity for society

<ns3:p>Advancements in the biological sciences have made it possible to manipulate life forms in unprecedented ways.. This activity, like working with pathogenic natural organisms is intrinsically dangerous. For this reason, countries have promoted the building of High Safety and High Containment Laboratories, classified as Biological Safety Levels 3 and 4. In this article I briefly summarize the major features of these laboratories, and exemplify some of the research that they host. I then highlight the possible dangers, and argue for the opportunity of a reduction of possibly dangerous research. I argue for more transparency and openness about activities that imply risks not only for those involved, but for human and environmental health as well.</ns3:p>

Authors

Institutions

Publication Details

Journal
F1000Research
Published
2025-12-05
DOI
https://doi.org/10.12688/f1000research.111073.2
Primary Topic
Bacillus and Francisella bacterial research
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

High-level biocontainment laboratories: risks and necessity for society

Monica Zoppè
F1000Research
Bacillus and Francisella bacterial research
article

High-level biocontainment laboratories: risks and necessity for society

Monica Zoppè
article en

Abstract

<ns3:p>Advancements in the biological sciences have made it possible to manipulate life forms in unprecedented ways.. This activity, like working with pathogenic natural organisms is intrinsically dangerous. For this reason, countries have promoted the building of High Safety and High Containment Laboratories, classified as Biological Safety Levels 3 and 4. In this article I briefly summarize the major features of these laboratories, and exemplify some of the research that they host. I then highlight the possible dangers, and argue for the opportunity of a reduction of possibly dangerous research. I argue for more transparency and openness about activities that imply risks not only for those involved, but for human and environmental health as well.</ns3:p>

F1000ResearchVol. 11
University of Milan (IT), Institute of Biophysics (BG)
Openalex Percentile: Top 65%
Bacillus and Francisella bacterial research
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.