Risk factor control in relation to mortality and life expectancy among people with type 2 diabetes: results from 3 nationwide cohort studies
Achievement of guideline targets for multiple risk factors was low among individuals with T2D in China, the USA, and the UK. Comprehensive management of multiple risk factors, particularly lifestyle factors, was associated with a substantial reduction in the life expectancy gap between those with and without T2D, underscoring the importance of guideline-based care and individualized management.
Authors
- Gang Liu (ORCID: https://orcid.org/0000-0002-1430-3016)
- An Pan
- Zixin Qiu (ORCID: https://orcid.org/0000-0001-6589-8454)
- Tingting Geng (ORCID: https://orcid.org/0000-0003-2309-7637)
- Pang Yao (ORCID: https://orcid.org/0000-0002-6875-7435)
- Oscar H. Franco (ORCID: https://orcid.org/0000-0002-4606-4929)
- Jun Liu (ORCID: https://orcid.org/0000-0002-3646-0004)
- Maigeng Zhou (ORCID: https://orcid.org/0000-0001-6402-6347)
- Rui Li (ORCID: https://orcid.org/0009-0000-5214-3132)
- Yanbo Zhang (ORCID: https://orcid.org/0000-0003-1054-9657)
- Kai Huang (ORCID: https://orcid.org/0000-0001-9276-796X)
- Frank Qian (ORCID: https://orcid.org/0000-0002-5579-3410)
- Eric B. Rimm
- JoAnn E. Manson
Institutions
- Brigham and Women's Hospital (US)
- Boston Medical Center (US)
- Albert Einstein College of Medicine (US)
- Harvard University (US)
- University Medical Center Utrecht (NL)
- Wuhan University (CN)
- University of Oxford (GB)
- National Center for Chronic and Noncommunicable Disease Control and Prevention (CN)
- Wuhan Union Hospital (CN)
- Huazhong University of Science and Technology Hospital (CN)
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Military Medical Research
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1186/s40779-025-00674-4
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsches Krebsforschungszentrum
- National Natural Science Foundation of China
- Huazhong University of Science and Technology
- National Science and Technology Major Project
- National Key Research and Development Program of China
- Fundamental Research Funds for the Central Universities