Persistent attenuation of lymphocyte subsets after mass SARS-CoV-2 infection
Our findings redefine SARS-CoV-2 infection as a condition of long-lasting immune compromise. The sustained subnormal lymphocytes-particularly in cardiovascular disease cohorts-highlight a key immunologic feature of long COVID and underscore the need for personalized care.
Authors
- Baobao Feng
- Yucan Li (ORCID: https://orcid.org/0000-0002-9778-9057)
- Miao Xu (ORCID: https://orcid.org/0000-0002-2981-9533)
- Zhengqi Jiang
- Xiao Zhen
- Heyu Ni (ORCID: https://orcid.org/0000-0002-7621-2945)
- Tichao Shan
- Jun Peng (ORCID: https://orcid.org/0000-0001-5764-6396)
- Fengjiao Han
Institutions
- St. Michael's Hospital (CA)
- Shandong Tumor Hospital (CN)
- Second Hospital of Shandong University (CN)
- Shandong Provincial Hospital (CN)
- Qilu Hospital of Shandong University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1016/j.ijid.2025.108287
- Citations
- 2
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 2.78
Funders
- Shandong University
- Qilu Hospital of Shandong University