Tumor Microenvironment Reprogramming via Copper-Enriched Black Phosphorus Nanoplatform for Cuproptosis-Sensitized Low-Dose Radioimmunotherapy
This work establishes a copper-based, low-dose radioimmunotherapy strategy. The BPNS@Cu-PEG nanoplatform presents a viable and potent strategy to counteract radioresistance and promote systemic antitumor immunity, potentially broadening the therapeutic application and safety profile of RIT.
Authors
- Zhichao Zheng (ORCID: https://orcid.org/0000-0002-4848-0862)
- Jin Wang (ORCID: https://orcid.org/0000-0001-8711-3507)
- Yutong Chen (ORCID: https://orcid.org/0000-0003-1728-6597)
- Weiyu Zhang (ORCID: https://orcid.org/0000-0002-8928-6636)
Institutions
- Fujian Medical University (CN)
- Jinan Maternity And Care Hospital (CN)
- Fujian Provincial Hospital (CN)
- Shandong Maternal and Child Health Hospital (CN)
- Shandong First Medical University (CN)
- Fuzhou University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/ijn.s563439
- Citations
- 1
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.67