Proteome profiling of extracellular vesicles-derived from hepatitis B virus-infected hepatocellular carcinoma cell lines identifies PDCD11 as a carrier of viral RNAs
Proteins enriched in the EVs-derived from HCC cells in presence of HBV may be further investigated to identify novel therapeutic targets within the TME of HBV-HCC. Our findings demonstrated the therapeutic potential of TFDP1-ASO and miR-1-3p, which could lead to new approaches in HBV-HCC treatment.
Authors
- Abhijit Chowdhury (ORCID: https://orcid.org/0000-0001-9198-4436)
- Soma Banerjee (ORCID: https://orcid.org/0000-0003-1828-9810)
- Soham Saha (ORCID: https://orcid.org/0000-0002-7012-4602)
- Subhas Das (ORCID: https://orcid.org/0000-0003-1325-5777)
- Amlan Kumar Das (ORCID: https://orcid.org/0000-0002-9295-3743)
- Simanti Datta (ORCID: https://orcid.org/0000-0002-1584-6952)
- Indrashish Dey
Institutions
- Institute of Post Graduate Medical Education and Research (IN)
- Indian Statistical Institute (IN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-12-05
- DOI
- https://doi.org/10.3389/fcell.2025.1643823
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00