Short- and Long-term Humoral Response of Immunosuppressed Children to SARS-CoV-2 BNT162b2 Vaccine

After 3 vaccine doses, immunosuppressed children demonstrate 6-month immune comparable to healthy children who received 2 doses. Despite a decline in humoral responses over time, there were no infections, supporting the effectiveness of current coronavirus disease 2019 vaccination strategies.

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Publication Details

Journal
The Pediatric Infectious Disease Journal
Published
2025-12-05
DOI
https://doi.org/10.1097/inf.0000000000005042
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
Field-Weighted Citation Impact
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article

Short- and Long-term Humoral Response of Immunosuppressed Children to SARS-CoV-2 BNT162b2 Vaccine

Santiago Salso, Sara Domínguez‐Rodríguez, Álvaro Ballesteros, Cinta Moraleda et al.
The Pediatric Infectious Disease Journal
SARS-CoV-2 and COVID-19 Research
article

Short- and Long-term Humoral Response of Immunosuppressed Children to SARS-CoV-2 BNT162b2 Vaccine

Santiago Salso, Sara Domínguez‐Rodríguez, Álvaro Ballesteros, Cinta Moraleda, Ángela Manzanares, Angelina Konnova, Carlo Giaquinto, Akshita Gupta, Matilda Berkell, Alfredo Tagarro, María del Carmen Plata, Sara Villanueva, An Hotterbeekx, Raquel Guillén, David Aguilera‐Alonso, Samir Kumar‐Singh, Irati Gastesi, Carlota Pinto, Manuel Oltra
article en

Abstract

After 3 vaccine doses, immunosuppressed children demonstrate 6-month immune comparable to healthy children who received 2 doses. Despite a decline in humoral responses over time, there were no infections, supporting the effectiveness of current coronavirus disease 2019 vaccination strategies.

The Pediatric Infectious Disease JournalVol. 45(3)
University of Antwerp (BE), Hospital General Universitario Gregorio Marañón (ES), Research Institute Hospital 12 de Octubre (ES), PENTA Foundation (IT), National Center for Women and Children’s Health, China CDC (CN), Leitat Technological Center (ES), Hospital Universitario del Henares (ES), Hospital Universitario Infanta Sofía (ES), Instituut voor Tropische Geneeskunde (BE), Universidad Europea de Madrid (ES)
Openalex Percentile: Top 55%
SARS-CoV-2 and COVID-19 Research
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