Long-term outcomes according to absolute value vs. percentage reduction in low-density lipoprotein cholesterol levels after acute myocardial infarction
This study involving 6,248 AMI patients demonstrated that the greater the LDL-C reduction from baseline, the lower the risk of MACE. However, there was no clear decreasing trend in the risk of MACE when absolute follow-up LDL-C levels were lowered from around 70 mg/dL.
Authors
- Jang Hoon Lee (ORCID: https://orcid.org/0000-0002-7101-0236)
- Sang Yeub Lee (ORCID: https://orcid.org/0000-0003-1386-349X)
- Seok Oh (ORCID: https://orcid.org/0000-0002-6193-2982)
- Jung-Ho Yang (ORCID: https://orcid.org/0000-0002-1581-8425)
- Young Joon Hong (ORCID: https://orcid.org/0000-0002-1831-8004)
- Ju-Seung Kwun (ORCID: https://orcid.org/0000-0002-9581-4060)
- Weon Kim (ORCID: https://orcid.org/0000-0003-1264-9870)
- Doo Sun Sim (ORCID: https://orcid.org/0000-0003-4162-7902)
- Jin‐Yong Hwang (ORCID: https://orcid.org/0000-0002-6632-7239)
- Min‐Ho Shin (ORCID: https://orcid.org/0000-0002-2217-5624)
- Youngkeun Ahn (ORCID: https://orcid.org/0000-0003-2022-9366)
- Min Chul Kim (ORCID: https://orcid.org/0000-0001-6026-1702)
- Ju Han Kim (ORCID: https://orcid.org/0000-0003-1522-9038)
- Young–Hoon Jeong (ORCID: https://orcid.org/0000-0002-1822-6601)
- Kyung Hoon Cho
- Joo-Yong Hahn
- Myung Ho Jeong (ORCID: https://orcid.org/0000-0003-4173-1494)
Institutions
- Gyeongsang National University (KR)
- Kyungpook National University Hospital (KR)
- New Generation University College (ET)
- Kyungpook National University (KR)
- Kyung Hee University (KR)
- Chonnam National University Hospital (KR)
- Veterans Health Service Medical Center (KR)
- Chonnam National University Hwasun Hospital (KR)
- National Medical Center (KR)
- Chung-Ang University Hospital (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-12-05
- DOI
- https://doi.org/10.3389/fcvm.2025.1653447
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00