Proteomics-driven screening of artemisinin-based combination ratios and mechanistic insights into Plasmodium berghei infection in mice
These findings provide mechanistic insights into artemisinin-associated immune potentiation. Moreover, we have proposed a novel ACT strategy targeting host-parasite interactions, offering a promising approach to circumvent emerging artemisinin resistance in <i>Plasmodium</i> species.
Authors
- Guimin Liu (ORCID: https://orcid.org/0000-0002-1409-789X)
- Jian‐Liang Li
- Hongmei Li (ORCID: https://orcid.org/0000-0003-2912-1837)
- Qiongjing Yuan
- Hai-Ru Huo
- Zongyuan Li
- Luqi Huang (ORCID: https://orcid.org/0000-0002-8435-8207)
- Jianhui Sun
- Liyu Hao
- Zeyue Yu
- Zhenru Shen
- Hanhui Huang
Institutions
- Shenyang Pharmaceutical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- China Academy of Chinese Medical Sciences (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-12-05
- DOI
- https://doi.org/10.3389/fimmu.2025.1716096
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00