Diagnostic accuracy of ultrasound models for assessment of ovarian tumors: systematic review and meta‐analysis

All approaches, except for the RMI, performed well and could be used to differentiate between benign and malignant ovarian tumors. Although SA with or without SR had the highest diagnostic performance, it is dependent on operator expertise. If a strategy independent of operator expertise is preferred, the ADNEX model is recommended. Because of the high sensitivity of the ADNEX model, the likelihood of missing malignancies is low. In postmenopausal women, however, the reduced specificity may warrant a higher cut-off, depending on how the impact of a false-positive test result is evaluated. © 2025 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.

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Publication Details

Journal
Ultrasound in Obstetrics and Gynecology
Published
2025-12-04
DOI
https://doi.org/10.1002/uog.70135
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Diagnostic accuracy of ultrasound models for assessment of ovarian tumors: systematic review and meta‐analysis

Jaklien C. Leemans, E. J. L. G. Delvaux, Christianne Lok, Peggy M. A. J. Geomini et al.
Ultrasound in Obstetrics and Gynecology
Ovarian cancer diagnosis and treatment
article

Diagnostic accuracy of ultrasound models for assessment of ovarian tumors: systematic review and meta‐analysis

Jaklien C. Leemans, E. J. L. G. Delvaux, Christianne Lok, Peggy M. A. J. Geomini, Esther Lems, Marlies Y. Bongers, BL Ramaekers, Anna H. Koch
article en

Abstract

All approaches, except for the RMI, performed well and could be used to differentiate between benign and malignant ovarian tumors. Although SA with or without SR had the highest diagnostic performance, it is dependent on operator expertise. If a strategy independent of operator expertise is preferred, the ADNEX model is recommended. Because of the high sensitivity of the ADNEX model, the likelihood of missing malignancies is low. In postmenopausal women, however, the reduced specificity may warrant a higher cut-off, depending on how the impact of a false-positive test result is evaluated. © 2025 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.

Ultrasound in Obstetrics and Gynecology
Radboud University Nijmegen (NL), Maastricht University Medical Centre (NL), Maastricht University (NL), Zero to Three (US), Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital (NL), Máxima Medisch Centrum (NL)
ZonMw
Openalex Percentile: Top 50%
Ovarian cancer diagnosis and treatment
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Diagnostic accuracy of ultrasound models for assessment of ovarian tumors: systematic review and meta‐analysis — Jaklien C. Leemans, E. J. L. G. Delvaux, et al. · Ultrasound in Obstetrics and Gynecology (2025) | TGRS Research Map | TGRS