Diagnostic accuracy of ultrasound models for assessment of ovarian tumors: systematic review and meta‐analysis
All approaches, except for the RMI, performed well and could be used to differentiate between benign and malignant ovarian tumors. Although SA with or without SR had the highest diagnostic performance, it is dependent on operator expertise. If a strategy independent of operator expertise is preferred, the ADNEX model is recommended. Because of the high sensitivity of the ADNEX model, the likelihood of missing malignancies is low. In postmenopausal women, however, the reduced specificity may warrant a higher cut-off, depending on how the impact of a false-positive test result is evaluated. © 2025 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.
Authors
- Jaklien C. Leemans (ORCID: https://orcid.org/0000-0002-0104-6751)
- E. J. L. G. Delvaux (ORCID: https://orcid.org/0000-0002-9782-1125)
- Christianne Lok (ORCID: https://orcid.org/0000-0001-8693-7299)
- Peggy M. A. J. Geomini (ORCID: https://orcid.org/0000-0002-1951-1076)
- Esther Lems (ORCID: https://orcid.org/0000-0002-4495-9622)
- Marlies Y. Bongers (ORCID: https://orcid.org/0000-0001-9276-9148)
- BL Ramaekers
- Anna H. Koch (ORCID: https://orcid.org/0000-0003-4947-3514)
Institutions
- Radboud University Nijmegen (NL)
- Maastricht University Medical Centre (NL)
- Maastricht University (NL)
- Zero to Three (US)
- Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital (NL)
- Máxima Medisch Centrum (NL)
Publication Details
- Journal
- Ultrasound in Obstetrics and Gynecology
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1002/uog.70135
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- ZonMw