Case Report: Exclusive localization of Leishman-Donovan bodies in neutrophils on peripheral blood smear in a patient with systemic lupus erythematosus

This case underscores the diagnostic challenge of VL in immunosuppressed patients. Symptom overlap with autoimmune disorders and atypical parasite locations (e.g., within neutrophils) can delay diagnosis. Morphological examination of blood and bone marrow remains crucial for detecting rare pathogens. In endemic areas, clinicians should routinely check for parasites within neutrophils to reduce misdiagnosis. Future studies should explore neutrophil-parasite interactions and improve infection monitoring strategies in immunocompromised hosts.

Authors

Institutions

Publication Details

Journal
Frontiers in Medicine
Published
2025-12-05
DOI
https://doi.org/10.3389/fmed.2025.1693178
Primary Topic
Blood disorders and treatments
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Case Report: Exclusive localization of Leishman-Donovan bodies in neutrophils on peripheral blood smear in a patient with systemic lupus erythematosus

Jia Li, Xuekai Liu, Ruixue Zhang, Mingjian Bai et al.
Frontiers in Medicine
Blood disorders and treatments
article

Case Report: Exclusive localization of Leishman-Donovan bodies in neutrophils on peripheral blood smear in a patient with systemic lupus erythematosus

Jia Li, Xuekai Liu, Ruixue Zhang, Mingjian Bai, Guowei Liang, Min He, Fucun Ma
article en

Abstract

This case underscores the diagnostic challenge of VL in immunosuppressed patients. Symptom overlap with autoimmune disorders and atypical parasite locations (e.g., within neutrophils) can delay diagnosis. Morphological examination of blood and bone marrow remains crucial for detecting rare pathogens. In endemic areas, clinicians should routinely check for parasites within neutrophils to reduce misdiagnosis. Future studies should explore neutrophil-parasite interactions and improve infection monitoring strategies in immunocompromised hosts.

Frontiers in MedicineVol. 12
Aerospace Center Hospital (CN)
Aerospace Center Hospital
Openalex Percentile: Top 60%
Blood disorders and treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.