Unraveling proteomic signatures and neuroinflammatory networks in a CCI rat model of early sciatica: insights for neuropathic pain mechanisms

The progression of early sciatic is closely associated with neuroinflammation triggered by the overexpression of inflammatory factors and nerve dysfunction mediated by neurotrophic-related proteins.

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Publication Details

Journal
Frontiers in Molecular Neuroscience
Published
2025-12-05
DOI
https://doi.org/10.3389/fnmol.2025.1674151
Primary Topic
Pain Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Unraveling proteomic signatures and neuroinflammatory networks in a CCI rat model of early sciatica: insights for neuropathic pain mechanisms

Zheng Xiao, Xiaojie Wang, Bin Jiang, Jinhui Song et al.
Frontiers in Molecular Neuroscience
Pain Mechanisms and Treatments
article

Unraveling proteomic signatures and neuroinflammatory networks in a CCI rat model of early sciatica: insights for neuropathic pain mechanisms

Zheng Xiao, Xiaojie Wang, Bin Jiang, Jinhui Song, Xingjuan Li, Yaqin Wen, Бо Лю, Yang Wang
article en

Abstract

The progression of early sciatic is closely associated with neuroinflammation triggered by the overexpression of inflammatory factors and nerve dysfunction mediated by neurotrophic-related proteins.

Frontiers in Molecular NeuroscienceVol. 18
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Wuhan National Laboratory for Optoelectronics (CN), Beijing Polytechnic (CN)
Openalex Percentile: Top 52%
Pain Mechanisms and Treatments
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