The impact of antidepressant use on antibiotic treatment outcomes in urinary tract infections and pneumonia: A population‐based cohort study
Antidepressants are associated with a modest rise in UTI treatment failure risk, possibly due to antibiotic resistance or other mechanisms. Despite this, their essential role in mental health management outweighs the small risk, emphasizing the need for judicious use, particularly in females and older adults. Further research is warranted to clarify underlying mechanisms.
Authors
- Shi‐Heng Wang (ORCID: https://orcid.org/0000-0002-8466-2698)
- Wei‐Lieh Huang (ORCID: https://orcid.org/0000-0001-5786-3366)
- Ming‐Shiang Wu (ORCID: https://orcid.org/0000-0002-1940-6428)
- Yi‐Chen Juan (ORCID: https://orcid.org/0000-0001-7646-896X)
- Chi‐Shin Wu (ORCID: https://orcid.org/0000-0003-2762-7295)
- Shu‐Chen Kuo (ORCID: https://orcid.org/0000-0002-6940-6450)
- Hui‐Ju Tsai (ORCID: https://orcid.org/0000-0002-5338-6117)
- Chen‐Yu Wang (ORCID: https://orcid.org/0000-0003-0498-2438)
Institutions
- National Health Research Institutes (TW)
- China Medical University (TW)
- National Tsing Hua University (TW)
- China Medical University Hospital (TW)
- National Taiwan University Hospital (TW)
Publication Details
- Journal
- Psychiatry and Clinical Neurosciences
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1111/pcn.70000
- Primary Topic
- Urinary Tract Infections Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00