Tanshinone IIA alleviates LPS-induced acute kidney injury by inhibiting RIP3/Nrf2-mediated oxidative stress
These findings suggest that Tan IIA protects against LPS-induced AKI by inhibiting RIP3 expression and restoring Nrf2-mediated antioxidant defenses, thereby attenuating oxidative stress and apoptosis.
Authors
- Xin Dong (ORCID: https://orcid.org/0000-0002-7112-0224)
- Gangyi Chen (ORCID: https://orcid.org/0009-0008-4180-3762)
- Chao Wang (ORCID: https://orcid.org/0000-0001-8452-1214)
- Shu Zhang (ORCID: https://orcid.org/0000-0002-8521-7916)
Institutions
- First Affiliated Hospital of Guangzhou University of Chinese Medicine (CN)
Publication Details
- Journal
- Renal Failure
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1080/0886022x.2025.2593719
- Primary Topic
- Traditional Chinese Medicine Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00