Development Of Ginkgolide B Nanocrystals Via Miniaturized Wet Bead Milling: A QbD Approach

A QbD-guided miniaturized wet bead milling process successfully produced stable GB-NC with markedly improved dissolution and cellular permeability. This presents a promising and scalable strategy to overcome the delivery challenges of GB, laying a foundation for developing effective oral formulations to enhance its bioavailability.

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Publication Details

Journal
Pakistan Journal of Pharmaceutical Sciences
Published
2025-12-05
DOI
https://doi.org/10.36721/pjps.2026.39.1.reg.14096.1
Primary Topic
Ginkgo biloba and Cashew Applications
Type
article
Field-Weighted Citation Impact
0.00

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article

Development Of Ginkgolide B Nanocrystals Via Miniaturized Wet Bead Milling: A QbD Approach

Pakistan Journal of Pharmaceutical Sciences
Ginkgo biloba and Cashew Applications
article

Development Of Ginkgolide B Nanocrystals Via Miniaturized Wet Bead Milling: A QbD Approach

article en

Abstract

A QbD-guided miniaturized wet bead milling process successfully produced stable GB-NC with markedly improved dissolution and cellular permeability. This presents a promising and scalable strategy to overcome the delivery challenges of GB, laying a foundation for developing effective oral formulations to enhance its bioavailability.

Pakistan Journal of Pharmaceutical SciencesVol. 39(1)
Shenyang Medical College (CN), Liaoning Jianzhu Vocational University (CN), Jinzhou Medical University (CN)
Liaoning University, Liaoning University of Traditional Chinese Medicine
Openalex Percentile: Top 45%
Ginkgo biloba and Cashew Applications
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