Adverse perinatal outcomes in twins: comparison of intertwin fetal size discordance <i>vs</i> singleton and twin fetal growth charts

Intertwin EFW discordance is a more reliable predictor of the composite outcome of stillbirth in at least one cotwin and/or iatrogenic early preterm birth in twin pregnancies than is EFW centile based on either singleton or twin-specific growth charts. This approach addresses the limitations of using different fetal growth reference charts that rely on arbitrary cut-offs. Following external validation, the use of intertwin EFW discordance prediction algorithms may potentially enhance risk stratification to improve clinical outcomes in twin pregnancies. © 2025 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.

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Publication Details

Journal
Ultrasound in Obstetrics and Gynecology
Published
2025-12-04
DOI
https://doi.org/10.1002/uog.70139
Citations
1
Primary Topic
Assisted Reproductive Technology and Twin Pregnancy
Type
article
Field-Weighted Citation Impact
3.49
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article

Adverse perinatal outcomes in twins: comparison of intertwin fetal size discordance vs singleton and twin fetal growth charts

B. Thilaganathan, Maria Giulia Ferrante, Miriam Lopian, Alessandra Familiari et al.
1 citations
Ultrasound in Obstetrics and Gynecology
Assisted Reproductive Technology and Twin Pregnancy
3.49
article

Adverse perinatal outcomes in twins: comparison of intertwin fetal size discordance vs singleton and twin fetal growth charts

B. Thilaganathan, Maria Giulia Ferrante, Miriam Lopian, Alessandra Familiari, Veronica Giorgione, T. Ghi, M. Brutto, Jacques C. Jani, Elisa Bevilacqua, Dominique A. Badr, Amarnath Bhide, Maurizio Trapani
article en
1 citations

Abstract

Intertwin EFW discordance is a more reliable predictor of the composite outcome of stillbirth in at least one cotwin and/or iatrogenic early preterm birth in twin pregnancies than is EFW centile based on either singleton or twin-specific growth charts. This approach addresses the limitations of using different fetal growth reference charts that rely on arbitrary cut-offs. Following external validation, the use of intertwin EFW discordance prediction algorithms may potentially enhance risk stratification to improve clinical outcomes in twin pregnancies. © 2025 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.

Ultrasound in Obstetrics and GynecologyVol. 67(1)
Università Cattolica del Sacro Cuore (IT), Université Libre de Bruxelles (BE), St George's, University of London (GB), St George’s University Hospitals NHS Foundation Trust (GB), Agostino Gemelli University Polyclinic (IT), Zero to Three (US)
Openalex Percentile: Top 6%
Assisted Reproductive Technology and Twin Pregnancy
3.49
DOIOpen Access PDFOpenAlex
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Adverse perinatal outcomes in twins: comparison of intertwin fetal size discordance <i>vs</i> singleton and twin fetal growth charts — B. Thilaganathan, Maria Giulia Ferrante, et al. · Ultrasound in Obstetrics and Gynecology (2025) | TGRS Research Map | TGRS