CHRNA5 D398N Mutation In Addiction: Pathogenic Insights And Therapeutic Discovery

These findings imply the D398N mutation predisposes to addiction susceptibility and that ligand 12 holds promise as a therapeutic target due to its high binding affinity and good pharmacological profiles.

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Publication Details

Journal
Pakistan Journal of Pharmaceutical Sciences
Published
2025-12-05
DOI
https://doi.org/10.36721/pjps.2026.39.1.reg.14072.1
Primary Topic
Nicotinic Acetylcholine Receptors Study
Type
article
Field-Weighted Citation Impact
0.00

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article

CHRNA5 D398N Mutation In Addiction: Pathogenic Insights And Therapeutic Discovery

Pakistan Journal of Pharmaceutical Sciences
Nicotinic Acetylcholine Receptors Study
article

CHRNA5 D398N Mutation In Addiction: Pathogenic Insights And Therapeutic Discovery

article en

Abstract

These findings imply the D398N mutation predisposes to addiction susceptibility and that ligand 12 holds promise as a therapeutic target due to its high binding affinity and good pharmacological profiles.

Pakistan Journal of Pharmaceutical SciencesVol. 39(1)
Northern Border University (SA), University of Lahore (PK), University of the Punjab (PK), Umm al-Qura University (SA), Farooq Hospital (PK)
Northern Border University
Openalex Percentile: Top 65%
Nicotinic Acetylcholine Receptors Study
DOIOpen Access PDFOpenAlex
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