L-arginine-induced chronic pancreatitis in mice: Evaluating effects of pirfenidone and simvastatin
Combination of pirfenidone and simvastatin demonstrated a synergistic therapeutic effect in reducing inflammation, fibrosis, and oxidative stress in an L-arginine-induced chronic pancreatitis mouse model, suggesting promise for chronic pancreatitis management.
Authors
- Bhavin Vyas (ORCID: https://orcid.org/0000-0001-6985-6083)
- Rajiv Mehta (ORCID: https://orcid.org/0000-0003-3197-4337)
- Bhargavi V. Desai (ORCID: https://orcid.org/0000-0002-0136-9251)
- Archi Patel
- Prakash Sojitra
- Dhvani Adhvaryu
- Simple Bhuptani
Institutions
- Veer Narmad South Gujarat University (IN)
- Yahoo (United Kingdom) (GB)
- Sardar Vallabhbhai National Institute of Technology Surat (IN)
- Hindu College of Pharmacy (IN)
- Activation Laboratories (CA)
Publication Details
- Journal
- World Journal of Gastrointestinal Pharmacology and Therapeutics
- Published
- 2025-12-05
- DOI
- https://doi.org/10.4292/wjgpt.v16.i4.111977
- Primary Topic
- Pancreatitis Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00