Interim analysis of promise, a clinical study combining the BET inhibitor OPN-2853 with ruxolitinib in patients with advanced myelofibrosis experiencing an inadequate response to ruxolitinib

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Journal
Blood
Published
2025-11-03
DOI
https://doi.org/10.1182/blood-2025-3794
Primary Topic
Protein Degradation and Inhibitors
Type
article
Field-Weighted Citation Impact
0.00
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article

Interim analysis of promise, a clinical study combining the BET inhibitor OPN-2853 with ruxolitinib in patients with advanced myelofibrosis experiencing an inadequate response to ruxolitinib

Steven Knapper, Jenny O’Nions, Adam J. Mead, Srinivasan Narayanan et al.
Blood
Protein Degradation and Inhibitors
article

Interim analysis of promise, a clinical study combining the BET inhibitor OPN-2853 with ruxolitinib in patients with advanced myelofibrosis experiencing an inadequate response to ruxolitinib

Steven Knapper, Jenny O’Nions, Adam J. Mead, Srinivasan Narayanan, Manish Jain, Claire Harrison, Patrick Harrington, Bethan Psaila, Frances Wadelin, Zsófia Brigitta Nagy, Mary Frances McMullin, R. G. Record, Rebecca Collings, Ayesha Begum, Rebecca H. Boucher, Kerry Inokuchi, Jackie Walling, Jiayi Wang, Sebastian Francis, B HUNTLEY
article en

Abstract

No abstract available for this paper.
BloodVol. 146(Supplement 1)
Birmingham City University (GB), Belfast Health and Social Care Trust (GB), University College Hospital (GB), Cardiff and Vale University Health Board (GB), Nottingham University Hospitals NHS Trust (GB), University College London Hospitals NHS Foundation Trust (GB), Guy's and St Thomas' NHS Foundation Trust (GB), Leeds Teaching Hospitals NHS Trust (GB), John Radcliffe Hospital (GB), University Hospital Southampton NHS Foundation Trust (GB), University of Oxford (GB), Sheffield Teaching Hospitals NHS Foundation Trust (GB), Mission Bio (United States) (US), Cancer Research UK Clinical Trials Unit (GB), Stem Cell Institute (PA), University College London (GB), University of Birmingham (GB)
Openalex Percentile: Top 65%
Protein Degradation and Inhibitors
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