Bioengineered hollow nanoflowers to synergistically modulate inflammation, angiogenesis and osteogenesis for enhancing repair of bone defects
Collectively, this work presents a versatile nanoplatform for reducing inflammation in early stage while subsequently promoting angiogenesis and osteogenesis, thereby offering a promising therapeutic strategy for bone regeneration under inflammatory conditions.
Authors
- Qingci Kong
- Zhengchuan Zhang (ORCID: https://orcid.org/0000-0002-8132-9427)
- HM Wong (ORCID: https://orcid.org/0000-0002-4902-4121)
- Xiaolin Yu (ORCID: https://orcid.org/0000-0003-0379-5622)
- Xinna Wang (ORCID: https://orcid.org/0000-0002-4156-7228)
- Xiaoyu Wang (ORCID: https://orcid.org/0000-0001-8245-6121)
- Feilong Deng (ORCID: https://orcid.org/0000-0002-6848-4174)
- Chaoran Fu
- Hongchen Sun (ORCID: https://orcid.org/0000-0002-5572-508X)
- Xiaoqiong Huang (ORCID: https://orcid.org/0000-0003-2354-0758)
- Pugeng Li
- Xuan Li (ORCID: https://orcid.org/0000-0001-6319-3020)
- LJ Jin (ORCID: https://orcid.org/0000-0003-4305-1337)
Institutions
- Sun Yat-sen University (CN)
- Education University of Hong Kong (HK)
- Stomatology Hospital (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1186/s12951-025-03891-0
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00