Multiparametric quantitative MRI combining SyMRI and MUSE-DWI for noninvasive stratification of HER2 status in breast cancer
SyMRI combined with MUSE-DWI enables noninvasive stratification of HER2 status in breast cancer. The proposed models demonstrated high diagnostic performance, good calibration, and favorable clinical utility in decision curve analysis, particularly for identifying HER2-low tumors. This imaging approach has the potential to complement biopsy and assist personalized treatment planning.
Authors
- Dongmei Ji (ORCID: https://orcid.org/0000-0003-0647-0153)
- Li Feng (ORCID: https://orcid.org/0000-0001-7658-1399)
- Wei Zhang (ORCID: https://orcid.org/0000-0002-5211-6094)
- Hao Zheng (ORCID: https://orcid.org/0009-0008-6133-0763)
- Kui Yang (ORCID: https://orcid.org/0000-0001-8883-8702)
- Hu Chang
Institutions
- Weifang Medical University (CN)
- Hubei University of Arts and Science (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-12-05
- DOI
- https://doi.org/10.3389/fonc.2025.1709170
- Primary Topic
- MRI in cancer diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00