Alterations in plasma cytokine profiles in generalized myasthenia gravis following different immunotherapeutic regimens
Cytokine levels were markedly elevated in the plasma of patients with GMG, indicating their potential involvement in disease-related immune dysregulation. Distinct treatment groups displayed different cytokine patterns, reflecting heterogeneous immunological states among patients receiving GC, TAC, or RTX. Collectively, these findings provide preliminary immunological insights into GMG and highlight the need for validation in larger, prospective studies.
Authors
- Chenjing Sun (ORCID: https://orcid.org/0000-0002-6162-383X)
- Yudan Liu (ORCID: https://orcid.org/0000-0002-7496-7033)
- Zhuangzhuang Ren
- Yufeng Zhang (ORCID: https://orcid.org/0000-0001-8702-5291)
- Yuping Chen (ORCID: https://orcid.org/0000-0001-8477-6321)
- Xihui Ma
- Feng Qiu (ORCID: https://orcid.org/0000-0003-3795-7976)
Institutions
- Chinese PLA General Hospital (CN)
- PLA 306 Hospital (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-12-05
- DOI
- https://doi.org/10.3389/fneur.2025.1728767
- Primary Topic
- Myasthenia Gravis and Thymoma
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chinese People’s Liberation Army