Early fluid therapy trajectories in acute pancreatitis: a retrospective cohort study
This study reveals five distinct dynamic trajectory patterns of early fluid therapy in AP. High-load sustained or fluctuating therapy significantly increases mortality risk. Dynamic monitoring of HCT (within a 35-44% safety window) and therapy trajectories offers a potential strategy to optimize fluid management.
Authors
- Huajing Ke (ORCID: https://orcid.org/0000-0002-2215-9907)
- Yaoyu Zou
- Shixuan Xiong
- Jianhua Wan (ORCID: https://orcid.org/0009-0009-6587-3770)
- Maobin Kuang
- Nonghua Lü (ORCID: https://orcid.org/0000-0003-4373-551X)
- Yin Zhu (ORCID: https://orcid.org/0000-0002-7561-2306)
- Xia Liang
- Wenhua He (ORCID: https://orcid.org/0000-0001-5499-1346)
Institutions
- First Affiliated Hospital of Jiangxi Medical College (CN)
Publication Details
- Journal
- World Journal of Emergency Surgery
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1186/s13017-025-00664-w
- Primary Topic
- Pancreatitis Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00