Association of genetic variants with extravascular complications and cytokine production in Takayasu arteritis: a cross-sectional study
SNPs in the chr21q22 region and elevated IL-17C levels may contribute to the pathophysiology of TAK-IBD-SpA comorbidity. These insights advance our understanding of the genetic and inflammatory mechanisms underlying extravascular complications in TAK.
Authors
- H. Tamai (ORCID: https://orcid.org/0000-0001-8784-2224)
- Yuko Kaneko (ORCID: https://orcid.org/0000-0003-2646-5765)
- Keiko Yoshimoto (ORCID: https://orcid.org/0000-0002-6491-267X)
- Mayu Magi
- Farzana Shumy (ORCID: https://orcid.org/0000-0002-1197-2839)
- Masaru Takeshita (ORCID: https://orcid.org/0000-0002-3281-6595)
- Kotaro Matsumoto (ORCID: https://orcid.org/0000-0003-2047-7626)
- Hiroto Yoshida (ORCID: https://orcid.org/0009-0001-5111-0125)
Institutions
- Keio University (JP)
- Chugai Pharma (United States) (US)
Publication Details
- Journal
- Rheumatology Advances in Practice
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1093/rap/rkaf133
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00