Telescoped continuous flow synthesis of benzimidazoles from <i>o</i> -phenylenediamines and carboxylic acids
A powerful telescoped continuous flow platform enables the 20-minute synthesis of diverse benzimidazoles with broad scope (32 examples) and gram-scale pharmaceutical applicability.
Authors
- Yong-Jun Zang
- Guosi Li (ORCID: https://orcid.org/0000-0003-4677-2666)
- Dong Liu (ORCID: https://orcid.org/0000-0001-6340-190X)
- Qilin Xu (ORCID: https://orcid.org/0000-0002-6372-6146)
- Zhihao Ma (ORCID: https://orcid.org/0000-0001-7412-5314)
- Yidong Zhong
- Fucheng Zhu (ORCID: https://orcid.org/0000-0002-6170-287X)
Institutions
- Shandong Tumor Hospital (CN)
- West Anhui University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1039/d5qo01526j
- Citations
- 1
- Primary Topic
- Innovative Microfluidic and Catalytic Techniques Innovation
- Type
- article
- Field-Weighted Citation Impact
- 0.67